اپوپروستنول

Treating high blood pressure in the blood vessels of the lungs (pulmonary arterial hypertension [PAH]) to improve exercise capacity.

Epoprostenol is a prostaglandin. It works by relaxing the blood vessels, which increases blood flow to the lungs.

Abnormal skin sensations (eg, burning, numbness, tingling); agitation; anxiety; back pain; diarrhea; dizziness; flu-like symptoms (eg, mild fever, mild chills, muscle aches); flushing; headache; loss of appetite; mild pain or redness at the injection site; muscle, bone, joint, or jaw pain; nausea; nervousness; stomach pain; sweating; tiredness; vomiting.

Tell your doctor or dentist that you take epoprostenol before you receive any medical or dental care, emergency care, or surgery.
Epoprostenol may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use epoprostenol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not suddenly stop using epoprostenol. You may experience a recurrence of PAH symptoms (eg, shortness of breath, dizziness, weakness). Discuss any questions or concerns with your doctor.
If your symptoms do not get better or if they get worse, check with your doctor.
Epoprostenol may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using epoprostenol while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use epoprostenol, check with your doctor. Discuss any possible risks to your baby.